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Patient Support

Resources to help your patients manage out-of-pocket expenses for ALOXI®. Including information about the Eisai Assistance Program and the ALOXI® Patient Assistance Program.

Eisai Assistance Program

The Eisai Assistance Program provides information to patients and healthcare professionals regarding the patient’s insurance benefits for coverage of ALOXI® (palonosetron HCI injection). In addition, our agents can also provide information relating to payor-specific policies for the coverage of ALOXI®, information regarding billing and coding requirements, and answer questions regarding financial assistance options. Call the Eisai Assistance Program today for all of your billing, coding, coverage and financial assistance questions.

Contact Us

Eisai Assistance Program

Phone: 1-866-61-EISAI (1-866-613-4724)
Fax: 1-866-57-EISAI (1-866-573-4724)
Monday – Friday, 8am – 8pm ET

ALOXI® Patient Assistance Program

Eisai has created the ALOXI® Patient Assistance Program for customers who need assistance paying for ALOXI®. This program provides ALOXI® at no cost to financially needy patients who meet program eligibility criteria. 

Depending on your patient's financial situation and clinical status, resources may be available to help with your patient’s costs for ALOXI®. You, patients, family members, advocates or case managers can assist patients in understanding what kind of support may be available by calling the Eisai Assistance Program.

You can download a copy of the ALOXI® Patient Assistance Program enrollment form below or call 1-866-61-EISAI (1-866-613-4724) for more information. The enrollment form, insurance information, financial documentation, signature of the prescribing healthcare professional, and patient's signature are required for the form to be considered complete.

Eisai reserves the right, at its sole discretion, to discontinue the Patient Assistance Program or change the qualifications at any time. All patient information remains confidential. Product supply for the program depends upon availability.

Find Information on Medicare Coverage

Learn about coverage alternatives for ALOXI® including Medicare coverage.

What is Chemotherapy-Induced Nausea?

ALOXI® is an anti-nausea medication that may help prevent nausea and vomiting associated with chemotherapy.

Eisai cannot guarantee payment of any claim. Coding, coverage, and reimbursement may vary significantly by payor, plan, patient, and setting of care. Actual coverage and reimbursement decisions are made by individual payors following the receipt of claims. For additional information, customers should consult with their payors for all relevant coding, reimbursement, and coverage requirements. It is the sole responsibility of the provider to select the proper code and ensure the accuracy of all claims used in seeking reimbursement. All services must be medically appropriate and properly supported in the patient medical record.


Indication in Adults

ALOXI® injection 0.25 mg/5ml is indicated in adults for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic chemotherapy, and the prevention of acute nausea and vomiting associated with initial and repeat courses of highly emetogenic chemotherapy.

Indication in Pediatrics

ALOXI® injection 20mcg/kg (max 1.5mg) is indicated in patients ≥ 1 month up to 17 years of age, for the prevention of acute nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including highly emetogenic chemotherapy.

Important Safety Information


  • ALOXI® is contraindicated in patients known to have hypersensitivity to the drug or any of its components
  • Warnings and Precautions

  • Hypersensitivity reactions, including anaphylaxis, have been reported with or without known hypersensitivity to other 5-HT3 receptor antagonists
  • Serotonin syndrome has been reported with 5-HT3 receptor antagonists alone, but particularly with the use of serotonergic drugs. Serotonin syndrome can be life threatening. Symptoms may include the following combination of signs and symptoms: mental status changes, autonomic instability, neuromuscular symptoms, seizures, and gastrointestinal symptoms. Patients should be monitored for the emergence of serotonin syndrome, and if symptoms occur, discontinue ALOXI® and initiate supportive treatment. Patients should be informed of the increased risk of serotonin syndrome, especially if ALOXI® is used concomitantly with other serotonergic drugs 
  • Adverse Reactions

  • In adults, the most commonly reported adverse drug reactions include headache (9%) and constipation (5%)
  • In pediatric patients, while they require a higher dose of palonosetron, the safety profile is consistent with the established profile in adults; however, adverse reactions were reported in < 0.1% of pediatric patients

  • For more information about ALOXI®, please see full Prescribing Information.

    This information is intended for use by our healthcare professionals in the United States only. Eisai Inc. recognizes the Internet is a global communications medium; however, laws, regulatory requirements and medical practices for pharmaceutical products vary from country to country. The Prescribing Information included here is not appropriate for use outside the United States. This site contains information about products that may have different product labeling in different countries. This site is published by Eisai Inc. 

    ALOXI® is a registered trademark of Helsinn Healthcare SA, Switzerland, used under license.
    Distributed and marketed by Eisai Inc and Helsinn Therapeutics (U.S.), Inc.