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Insurance Coverage Information

ALOXI® is generally covered by Insurance Companies, Medicare and Medicaid. Coverage may change based on the specific type of insurance you have and your Healthcare Provider. Ask your Healthcare Provider about how your insurance will cover ALOXI®

Eisai offers financial assistance to eligible patients who can’t afford ALOXI®.  Talk to your Healthcare Provider about what assistance options may be available to you. The Eisai Assistance Program can assist you with understanding your options and can be reached at 1-866-61-EISAI or 1-866-613-4724.

Commercial Insurance

Commercial insurance companies include organizations such as health maintenance organization (HMO) plans, managed care organizations, indemnity plans and others. Many of these provide coverage for ALOXI® (palonosetron HCI injection). However, specific coverage requirements and limits depend on a patient’s benefits and will vary based on your plan type and healthcare provider.  Contact your healthcare provider to understand what your coverage for your ALOXI® treatments will be.


Medicare is the federal health insurance program for people who are 65 or older, certain younger people with disabilities, and people with End-Stage Renal Disease.  Part B covers certain doctors' services, outpatient care, medical supplies, and preventive services including your ALOXI® treatment.  Contact your Healthcare Provider for assistance in understanding how Medicare may cover your ALOXI® treatments. 


Medicaid is a joint federal and state program that helps with medical costs for some people with limited income and resources. Each state sets its own coverage and eligibility rules for its Medicaid program. ALOXI® (palonosetron HCI injection) is eligible for coverage under most state Medicaid programs. However, coverage and patient out of pocket costs will vary from state to state. Contact your Healthcare Provider for assistance in determining how your state Medicaid plan will cover ALOXI®.

Getting Coverage

Understanding your insurance coverage is the first step in getting your treatments covered. In most cases, this is going to start with your healthcare provider contacting your insurance company. Once your coverage has been established you can explore your alternatives. If your insurance covers most of your treatment costs, there may be assistance paying the copays on your medications. If you do not have coverage, you may be eligible for government assistance such as Medicare or Medicaid.  If you do not qualify for these programs Eisai offers a Patient Assistance Program that may help. Contact your Healthcare Provider to start understanding your coverage needs and determine eligibility for assistance.

Do You Need Financial Assistance?

Programs run by Eisai and Assistance Foundations are available to manage out-of-pocket costs.

What is Chemotherapy-Induced Nausea?

ALOXI® is an anti-nausea medication that may help prevent nausea and vomiting associated with chemotherapy.

Eisai cannot guarantee payment of any claim. Coding, coverage, and reimbursement may vary significantly by payor, plan, patient, and setting of care. Actual coverage and reimbursement decisions are made by individual payors following the receipt of claims. For additional information, customers should consult with their payors for all relevant coding, reimbursement, and coverage requirements. It is the sole responsibility of the provider to select the proper code and ensure the accuracy of all claims used in seeking reimbursement. All services must be medically appropriate and properly supported in the patient medical record.

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Indication in Adults

ALOXI® injection is used in adults to help prevent nausea and vomiting on the day of chemotherapy that is highly likely to cause nausea and vomiting, and up to 5 days following chemotherapy that is moderately likely to cause nausea and vomiting.

Indication in Pediatrics

ALOXI® injection is used in children 1 month old to less than 17 years of age to help prevent nausea and vomiting on the day of chemotherapy that is moderately or highly likely to cause nausea and vomiting.

Important Safety Information

  • ALOXI® can cause allergic reactions that can be serious. Tell your doctor or nurse right away if you have any of these following symptoms of a serious allergic reaction: hives, swelling of the face, trouble breathing and chest pain
  • The most common side effects of ALOXI® in adults are headache and constipation
  • Tell your doctor or nurse if you are taking other medications or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed

  • For more information about ALOXI®, talk to your doctor or see full prescribing information Prescribing Information.

    ALOXI® is available by prescription only.

    You are encouraged to report negative side effects of prescription drugs to the FDA.
    Visit http://www.FDA.gov/medwatch or 1-800-FDA-1088.